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Sequence of Gating Charge Movement and Pore Gating in hERG Activation and Deactivation Pathways

K(V)11.1 voltage-gated K(+) channels are noted for unusually slow activation, fast inactivation, and slow deactivation kinetics, which tune channel activity to provide vital repolarizing current during later stages of the cardiac action potential. The bulk of charge movement in human ether-a-go-go-r...

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書目詳細資料
發表在:Biophys J
Main Authors: Goodchild, Samuel J., Macdonald, Logan C., Fedida, David
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375626/
https://ncbi.nlm.nih.gov/pubmed/25809256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.02.014
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