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Sequence of Gating Charge Movement and Pore Gating in hERG Activation and Deactivation Pathways
K(V)11.1 voltage-gated K(+) channels are noted for unusually slow activation, fast inactivation, and slow deactivation kinetics, which tune channel activity to provide vital repolarizing current during later stages of the cardiac action potential. The bulk of charge movement in human ether-a-go-go-r...
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| Gepubliceerd in: | Biophys J |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Biophysical Society
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4375626/ https://ncbi.nlm.nih.gov/pubmed/25809256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.02.014 |
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