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Evidence for novel caffeine and Ca(2+) binding sites on the lobster skeletal ryanodine receptor

1. The effects of Ca(2+), ATP and caffeine on the gating of lobster skeletal muscle ryanodine receptors (RyR) was investigated after reconstitution of the channels into planar phospholipid bilayers and by using [(3)H]-ryanodine binding studies. 2. The single channel studies reveal that the EC(50) (6...

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Main Authors: Zhang, Jin Jun, Williams, Alan J, Sitsapesan, Rebecca
格式: Artigo
語言:Inglês
出版: 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571222/
https://ncbi.nlm.nih.gov/pubmed/10193789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702400
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