Investigation of Inhibition Mechanism of Chemokine Receptor CCR5 by Micro-second Molecular Dynamics Simulations

Por Salmas, Ramin Ekhteiari, Yurtsever, Mine, Durdagi, Serdar
Publicado no Sci Rep (2015)

Structural modeling of the N-terminal signal–receiving domain of IκBα

Por Yazdi, Samira, Durdagi, Serdar, Naumann, Michael, Stein, Matthias
Publicado no Front Mol Biosci (2015)

Cholesterol up-regulates neuronal G protein-gated inwardly rectifying potassium (GIRK) channel activity in the hippocampus

Por Bukiya, Anna N., Durdagi, Serdar, Noskov, Sergei, Rosenhouse-Dantsker, Avia
Publicado no J Biol Chem (2017)

Identification of Novel Cholesterol-binding Regions in Kir2 Channels

Por Rosenhouse-Dantsker, Avia, Noskov, Sergei, Durdagi, Serdar, Logothetis, Diomedes E., Levitan, Irena
Publicado em 2013

Rehabilitating drug-induced long-QT promoters: In-silico design of hERG-neutral cisapride analogues with retained pharmacological activity

Por Durdagi, Serdar, Randall, Trevor, Duff, Henry J, Chamberlin, Adam, Noskov, Sergei Y
Publicado em 2014

Recent Developments of Carbonic Anhydrase Inhibitors as Potential Drugs

Por Iqbal, Jamshed, Al-Rashida, Mariya, Durdagi, Serdar, Alterio, Vincenzo, Di Fiore, Anna
Publicado no Biomed Res Int (2015)

Molecular Simulations of Solved Co-crystallized X-Ray Structures Identify Action Mechanisms of PDEδ Inhibitors

Por Salmas, Ramin Ekhteiari, Mestanoglu, Mert, Yurtsever, Mine, Noskov, Sergei Y., Durdagi, Serdar
Publicado no Biophys J (2015)

Structural Refinement of the hERG1 Pore and Voltage-Sensing Domains with ROSETTA-Membrane and Molecular Dynamics Simulations

Por Subbotina, Julia, Yarov-Yarovoy, Vladimir, Lees-Miller, James, Durdagi, Serdar, Guo, Jiqing, Duff, Henry J., Noskov, Sergei Yu.
Publicado em 2010

Role of the pH in state-dependent blockade of hERG currents

Por Wang, Yibo, Guo, Jiqing, Perissinotti, Laura L., Lees-Miller, James, Teng, Guoqi, Durdagi, Serdar, Duff, Henry J., Noskov, Sergei Yu.
Publicado no Sci Rep (2016)

Structure Driven Design of Novel Human Ether-A-Go-Go-Related-Gene Channel (hERG1) Activators

Por Guo, Jiqing, Durdagi, Serdar, Changalov, Mohamed, Perissinotti, Laura L., Hargreaves, Jason M., Back, Thomas G., Noskov, Sergei Y., Duff, Henry J.
Publicado em 2014

NS1643 Interacts around L529 of hERG to Alter Voltage Sensor Movement on the Path to Activation

Por Guo, Jiqing, Cheng, Yen May, Lees-Miller, James P., Perissinotti, Laura L., Claydon, Tom W., Hull, Christina M., Thouta, Samrat, Roach, Daniel E., Durdagi, Serdar, Noskov, Sergei Y., Duff, Henry J.
Publicado no Biophys J (2015)