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Investigation of Inhibition Mechanism of Chemokine Receptor CCR5 by Micro-second Molecular Dynamics Simulations

Chemokine receptor 5 (CCR5) belongs to G protein coupled receptors (GPCRs) and plays an important role in treatment of human immunodeficiency virus (HIV) infection since HIV uses CCR5 protein as a co-receptor. Recently, the crystal structure of CCR5-bound complex with an approved anti-retroviral dru...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Salmas, Ramin Ekhteiari, Yurtsever, Mine, Durdagi, Serdar
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547396/
https://ncbi.nlm.nih.gov/pubmed/26299310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13180
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