Cholesterol up-regulates neuronal G protein-gated inwardly rectifying potassium (GIRK) channel activity in the hippocampus

Hypercholesterolemia is a well known risk factor for the development of neurodegenerative disease. However, the underlying mechanisms are mostly unknown. In recent years, it has become increasingly evident that cholesterol-driven effects on physiology and pathophysiology derive from its ability to a...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Bukiya, Anna N., Durdagi, Serdar, Noskov, Sergei, Rosenhouse-Dantsker, Avia
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Molecular Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391746/
https://ncbi.nlm.nih.gov/pubmed/28213520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.753350
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