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Dual activation of neuronal G protein-gated inwardly rectifying potassium (GIRK) channels by cholesterol and alcohol

Activation of G protein-gated inwardly rectifying potassium (GIRK) channels leads to a hyperpolarization of the neuron’s membrane potential, providing an important component of inhibition in the brain. In addition to the canonical G protein-activation pathway, GIRK channels are activated by small mo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Glaaser, Ian W., Slesinger, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496853/
https://ncbi.nlm.nih.gov/pubmed/28676630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04681-x
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