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Molecular mechanism underlying ethanol activation of G-protein–gated inwardly rectifying potassium channels

Alcohol (ethanol) produces a wide range of pharmacological effects on the nervous system through its actions on ion channels. The molecular mechanism underlying ethanol modulation of ion channels is poorly understood. Here we used a unique method of alcohol-tagging to demonstrate that alcohol activa...

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Autors principals: Bodhinathan, Karthik, Slesinger, Paul A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831446/
https://ncbi.nlm.nih.gov/pubmed/24145411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311406110
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