Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K(+) channels
Local anesthetics, commonly used for treating cardiac arrhythmias, pain, and seizures, are best known for their inhibitory effects on voltage-gated Na(+) channels. Cardiovascular and central nervous system toxicity are unwanted side-effects from local anesthetics that cannot be attributed to the inh...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33494/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11353868/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.111447798 |
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