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Activation of heteromeric G protein-gated inward rectifier K(+) channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons

G protein-gated inward rectifier K(+) channel subunits 1–4 (GIRK1–4) have been cloned from neuronal and atrial tissue and function as heterotetramers. To examine the inhibition of neuronal excitation by GIRKs, we overexpressed GIRKs in cultured hippocampal neurons from 18 day rat embryos, which norm...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ehrengruber, Markus U., Doupnik, Craig A., Xu, Youfeng, Garvey, Justine, Jasek, Mark C., Lester, Henry A., Davidson, Norman
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences of the USA 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC21286/
https://ncbi.nlm.nih.gov/pubmed/9192693
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