Activation of heteromeric G protein-gated inward rectifier K(+) channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons
G protein-gated inward rectifier K(+) channel subunits 1–4 (GIRK1–4) have been cloned from neuronal and atrial tissue and function as heterotetramers. To examine the inhibition of neuronal excitation by GIRKs, we overexpressed GIRKs in cultured hippocampal neurons from 18 day rat embryos, which norm...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21286/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9192693/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.13.7070 |
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