Alcohol modulation of G-protein-gated inwardly rectifying potassium channels: from binding to therapeutics

Alcohol (ethanol)-induced behaviors may arise from direct interaction of alcohol with discrete protein cavities within brain proteins. Recent structural and biochemical studies have provided new insights into the mechanism of alcohol-dependent activation of G protein-gated inwardly rectifying potass...

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Bibliographic Details
Main Authors: Bodhinathan, Karthik, Slesinger, Paul A.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933770/
https://ncbi.nlm.nih.gov/pubmed/24611054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00076
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