Folate binding site of flavin-dependent thymidylate synthase

The DNA nucleotide thymidylate is synthesized by the enzyme thymidylate synthase, which catalyzes the reductive methylation of deoxyuridylate using the cofactor methylene-tetrahydrofolate (CH(2)H(4)folate). Most organisms, including humans, rely on the thyA- or TYMS-encoded classic thymidylate synth...

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Detaylı Bibliyografya
Asıl Yazarlar: Koehn, Eric M., Perissinotti, Laura L., Moghram, Salah, Prabhakar, Arjun, Lesley, Scott A., Mathews, Irimpan I., Kohen, Amnon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465422/
https://ncbi.nlm.nih.gov/pubmed/23019356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206077109
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