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Trapping of an intermediate in the reaction catalyzed by flavin-dependent thymidylate synthase (FDTS)

Thymidylate is a DNA nucleotide that is essential to all organisms and is synthesized by the enzyme thymidylate synthase (TSase). Several human pathogens rely on an alternative flavin-dependent thymidylate synthase (FDTS), which differs from the human TSase both in structure and molecular mechanism....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mishanina, Tatiana V., Koehn, Eric M., Conrad, John A., Palfey, Bruce A., Lesley, Scott A., Kohen, Amnon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296878/
https://ncbi.nlm.nih.gov/pubmed/22295882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2120822
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