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Substrate Activation in Flavin-Dependent Thymidylate Synthase
[Image: see text] Thymidylate is a critical DNA nucleotide that has to be synthesized in cells de novo by all organisms. Flavin-dependent thymidylate synthase (FDTS) catalyzes the final step in this de novo production of thymidylate in many human pathogens, but it is absent from humans. The FDTS rea...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2014
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121000/ https://ncbi.nlm.nih.gov/pubmed/25025487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja506108b |
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