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Flavin-dependent thymidylate synthase: N5 of flavin as a Methylene carrier
Thymidylate is synthesized de novo in all living organisms for replication of genomes. The chemical transformation is reductive methylation of deoxyuridylate at C5 to form deoxythymidylate. All eukaryotes including humans complete this well-understood transformation with thymidylate synthase utilizi...
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| Published in: | Arch Biochem Biophys |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728703/ https://ncbi.nlm.nih.gov/pubmed/28821425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2017.08.011 |
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