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Substrate Activation in Flavin-Dependent Thymidylate Synthase

[Image: see text] Thymidylate is a critical DNA nucleotide that has to be synthesized in cells de novo by all organisms. Flavin-dependent thymidylate synthase (FDTS) catalyzes the final step in this de novo production of thymidylate in many human pathogens, but it is absent from humans. The FDTS rea...

詳細記述

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書誌詳細
主要な著者: Mishanina, Tatiana V., Corcoran, John M., Kohen, Amnon
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2014
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121000/
https://ncbi.nlm.nih.gov/pubmed/25025487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja506108b
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