4-(4-(Dimethylamino)phenyl)-1-methylpyridinium (APP(+)) Is a Fluorescent Substrate for the Human Serotonin Transporter

Monoamine transporters terminate synaptic neurotransmission and are molecular targets for antidepressants and psychostimulants. Fluorescent reporters can monitor real-time transport and are amenable for high-throughput screening. However, until now, their use has mostly been successful to study the...

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Bibliographische Detailangaben
Hauptverfasser: Solis, Ernesto, Zdravkovic, Igor, Tomlinson, Ian D., Noskov, Sergei Y., Rosenthal, Sandra J., De Felice, Louis J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308769/
https://ncbi.nlm.nih.gov/pubmed/22291010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.267757
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