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Refinement of a cryo-EM structure of hERG: Bridging structure and function
The human-ether-a-go-go-related gene (hERG) encodes the voltage-gated potassium channel (KCNH2 or Kv11.1, commonly known as hERG). This channel plays a pivotal role in the stability of phase 3 repolarization of the cardiac action potential. Although a high-resolution cryo-EM structure is available f...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7896098/ https://ncbi.nlm.nih.gov/pubmed/33476597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.01.011 |
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