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A Three-Dimensional Model of a Group II Intron RNA and Its Interaction with the Intron-Encoded Reverse Transcriptase

Group II introns are self-splicing ribozymes believed to be the ancestors of spliceosomal introns. Many group II introns encode reverse transcriptases that promote both RNA splicing and intron mobility to new genomic sites. Here we used a circular permutation and cross-linking method to establish si...

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Detalhes bibliográficos
Main Authors: Dai, Lixin, Chai, Dinggeng, Gu, Shan-Qing, Gabel, Jesse, Noskov, Sergei Y., Blocker, Forrest J. H., Lambowitz, Alan M., Zimmerly, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724966/
https://ncbi.nlm.nih.gov/pubmed/18424209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.04.001
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