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Inter-species variation in monovalent anion substrate selectivity and inhibitor sensitivity in the sodium iodide symporter (NIS)
The sodium iodide symporter (NIS) transports iodide, which is necessary for thyroid hormone production. NIS also transports other monovalent anions such as tetrafluoroborate (BF(4)(-)), pertechnetate (TcO(4)(-)), and thiocyanate (SCN(-)), and is competitively inhibited by perchlorate (ClO(4)(-)). Ho...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7034854/ https://ncbi.nlm.nih.gov/pubmed/32084174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229085 |
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