Mapping of Ion and Substrate Binding Sites in Human Sodium Iodide Symporter (hNIS)

The human sodium iodide symporter (hNIS) is a theranostic reporter gene which concentrates several clinically approved SPECT and PET radiotracers and plays an essential role for the synthesis of thyroid hormones as an iodide transporter in the thyroid gland. Development of hNIS mutants which could e...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Chem Inf Model
Main Authors: Zhekova, Hristina R., Sakuma, Toshie, Johnson, Ryan, Concilio, Susanna C., Lech, Patrycja J., Zdravkovic, Igor, Damergi, Mirna, Suksanpaisan, Lukkana, Peng, Kah-Whye, Russell, Stephen J., Noskov, Sergei
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249729/
https://ncbi.nlm.nih.gov/pubmed/32134653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.9b01114
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