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Mapping of Ion and Substrate Binding Sites in Human Sodium Iodide Symporter (hNIS)

The human sodium iodide symporter (hNIS) is a theranostic reporter gene which concentrates several clinically approved SPECT and PET radiotracers and plays an essential role for the synthesis of thyroid hormones as an iodide transporter in the thyroid gland. Development of hNIS mutants which could e...

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Detalhes bibliográficos
Publicado no:J Chem Inf Model
Main Authors: Zhekova, Hristina R., Sakuma, Toshie, Johnson, Ryan, Concilio, Susanna C., Lech, Patrycja J., Zdravkovic, Igor, Damergi, Mirna, Suksanpaisan, Lukkana, Peng, Kah-Whye, Russell, Stephen J., Noskov, Sergei
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249729/
https://ncbi.nlm.nih.gov/pubmed/32134653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.9b01114
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