Mapping of Ion and Substrate Binding Sites in Human Sodium Iodide Symporter (hNIS)

The human sodium iodide symporter (hNIS) is a theranostic reporter gene which concentrates several clinically approved SPECT and PET radiotracers and plays an essential role for the synthesis of thyroid hormones as an iodide transporter in the thyroid gland. Development of hNIS mutants which could e...

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Bibliografiska uppgifter
I publikationen:J Chem Inf Model
Huvudupphovsmän: Zhekova, Hristina R., Sakuma, Toshie, Johnson, Ryan, Concilio, Susanna C., Lech, Patrycja J., Zdravkovic, Igor, Damergi, Mirna, Suksanpaisan, Lukkana, Peng, Kah-Whye, Russell, Stephen J., Noskov, Sergei
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249729/
https://ncbi.nlm.nih.gov/pubmed/32134653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.9b01114
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