An Automated Image Analysis System to Quantify Endosomal Tubulation

Por Newton, Timothy M., Reid, Evan
Publicado no PLoS One (2016)

Sterol metabolism regulates neuroserpin polymer degradation in the absence of the unfolded protein response in the dementia FENIB

Por Roussel, Benoit D., Newton, Timothy M., Malzer, Elke, Simecek, Nikol, Haq, Imran, Thomas, Sally E., Burr, Marian L., Lehner, Paul J., Crowther, Damian C., Marciniak, Stefan J., Lomas, David A.
Publicado em 2013

Defects in ER–endosome contacts impact lysosome function in hereditary spastic paraplegia

Por Allison, Rachel, Edgar, James R., Pearson, Guy, Rizo, Tania, Newton, Timothy, Günther, Sven, Berner, Fiamma, Hague, Jennifer, Connell, James W., Winkler, Jürgen, Lippincott-Schwartz, Jennifer, Beetz, Christian, Winner, Beate, Reid, Evan
Publicado no J Cell Biol (2017)

p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer

Por Tentler, John J., Ionkina, Anastasia, Tan, Aik Choon, Newton, Timothy P., Pitts, Todd M., Glogowska, Magdalena J., Kabos, Peter, Sartorius, Carol A., Sullivan, Kelly D., Espinosa, Joaquin M., Eckhardt, S. Gail, Diamond, Jennifer R.
Publicado no Mol Cancer Ther (2015)

Overcoming IGF1R/IR Resistance Through Inhibition of MEK Signaling in Colorectal Cancer Models

Por Flanigan, Sara A., Pitts, Todd M., Newton, Timothy P., Kulikowski, Gillian N., Tan, Aik Choon, McManus, Martine C., Spreafico, Anna, Kachaeva, Maria I., Selby, Heather M., Tentler, John J., Eckhardt, S. Gail, Leong, Stephen
Publicado em 2013

Predictive Biomarkers of Sensitivity to the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Preclinical Breast Cancer Models

Por Diamond, Jennifer R., Eckhardt, S. Gail, Tan, Aik Choon, Newton, Timothy P., Selby, Heather M., Brunkow, Kelsey L., Kachaeva, Maria I., Varella-Garcia, Marileila, Pitts, Todd M., Bray, Mark R., Fletcher, Graham C., Tentler, John J.
Publicado em 2012

Dual Pharmacological Targeting of the MAP Kinase and PI3K/mTOR Pathway in Preclinical Models of Colorectal Cancer

Por Pitts, Todd M., Newton, Timothy P., Bradshaw-Pierce, Erica L., Addison, Rebecca, Arcaroli, John J., Klauck, Peter J., Bagby, Stacey M., Hyatt, Stephanie L., Purkey, Alicia, Tentler, John J., Tan, Aik Choon, Messersmith, Wells A., Eckhardt, S. Gail, Leong, Stephen
Publicado no PLoS One (2014)

Mechanistic basis of an epistatic interaction reducing age at onset in hereditary spastic paraplegia

Por Newton, Timothy, Allison, Rachel, Edgar, James R, Lumb, Jennifer H, Rodger, Catherine E, Manna, Paul T, Rizo, Tania, Kohl, Zacharias, Nygren, Anders O H, Arning, Larissa, Schüle, Rebecca, Depienne, Christel, Goldberg, Lisa, Frahm, Christiane, Stevanin, Giovanni, Durr, Alexandra, Schöls, Ludger, Winner, Beate, Beetz, Christian, Reid, Evan
Publicado no Brain (2018)

Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer

Por Spreafico, Anna, Tentler, John J., Pitts, Todd M., Tan, Aik Choon, Gregory, Mark A., Arcaroli, John J., Klauck, Peter J., McManus, Martine C., Hansen, Ryan J., Kim, Jihye, Micel, Lindsey N., Selby, Heather M., Newton, Timothy P., McPhillips, Kelly, Gustafson, Daniel L., DeGregori, James V., Messersmith, Wells A., Winn, Robert A., Eckhardt, S. Gail
Publicado em 2013