Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

Por Bagby, Stacey, Messersmith, Wells A., Pitts, Todd M., Capasso, Anna, Varella-­Garcia, Marileila, Klauck, Peter J., Kim, Jihye, Tan, Aik-Choon, Eckhardt, S. Gail, Tentler, John J., Arcaroli, John
Publicado no J Vis Exp (2016)

An integrated bioinformatics analysis to dissect kinase dependency in triple negative breast cancer

Por Ryall, Karen A, Kim, Jihye, Klauck, Peter J, Shin, Jimin, Yoo, Minjae, Ionkina, Anastasia, Pitts, Todd M, Tentler, John J, Diamond, Jennifer R, Eckhardt, S Gail, Heasley, Lynn E, Kang, Jaewoo, Tan, Aik Choon
Publicado no BMC Genomics (2015)

Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts

Por Lieu, Christopher H., Klauck, Peter J., Henthorn, Patrick K., Tentler, John J., Tan, Aik-Choon, Spreafico, Anna, Selby, Heather M., Britt, Blair C., Bagby, Stacey M., Arcaroli, John J., Messersmith, Wells A., Pitts, Todd M., Eckhardt, S. Gail
Publicado no Oncotarget (2015)

Dual Pharmacological Targeting of the MAP Kinase and PI3K/mTOR Pathway in Preclinical Models of Colorectal Cancer

Por Pitts, Todd M., Newton, Timothy P., Bradshaw-Pierce, Erica L., Addison, Rebecca, Arcaroli, John J., Klauck, Peter J., Bagby, Stacey M., Hyatt, Stephanie L., Purkey, Alicia, Tentler, John J., Tan, Aik Choon, Messersmith, Wells A., Eckhardt, S. Gail, Leong, Stephen
Publicado no PLoS One (2014)

Antitumor Activity of the MEK Inhibitor TAK-733 Against Melanoma Cell Lines and Patient-Derived Tumor Explants

Por Micel, Lindsey N., Tentler, John J., Tan, Aik Choon, Selby, Heather M., Brunkow, Kelsey L., Robertson, Kelli M., Davis, S. Lindsey, Klauck, Peter J., Pitts, Todd M., Gangolli, Esha, Fabrey, Robyn, O'Connell, Shawn M., Vincent, Patrick W., Eckhardt, S. Gail
Publicado no Mol Cancer Ther (2014)

Targeting the Protein Ubiquitination Machinery in Melanoma by the NEDD8-Activating Enzyme Inhibitor Pevonedistat (MLN4924)

Por Wong, Kit Man, Micel, Lindsey N., Selby, Heather M., Tan, Aik Choon, Pitts, Todd M., Bagby, Stacey M., Spreafico, Anna, Klauck, Peter J., Blakemore, Stephen J., Smith, Peter F., McDonald, Alice, Berger, Allison, Tentler, John J., Eckhardt, S. Gail
Publicado no Invest New Drugs (2016)

Combined inhibition of MEK and Aurora A kinase in KRAS/PIK3CA double-mutant colorectal cancer models

Por Davis, S. Lindsey, Robertson, Kelli M., Pitts, Todd M., Tentler, John J., Bradshaw-Pierce, Erica L., Klauck, Peter J., Bagby, Stacey M., Hyatt, Stephanie L., Selby, Heather M., Spreafico, Anna, Ecsedy, Jeffrey A., Arcaroli, John J., Messersmith, Wells A., Tan, Aik Choon, Eckhardt, S. Gail
Publicado no Front Pharmacol (2015)

Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer

Por Pitts, Todd M., Bradshaw, Erica L., Bagby, Stacey M., Hyatt, Stephanie L., Selby, Heather M., Spreafico, Anna, Tentler, John J., McPhillips, Kelly, Klauck, Peter J., Capasso, Anna, Diamond, Jennifer R., Davis, S. Lindsey, Tan, Aik Choon, Arcaroli, John J., Purkey, Alicia, Messersmith, Wells A., Ecsedy, Jeffery A., Eckhardt, S. Gail
Publicado no Oncotarget (2016)

Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer

Por Spreafico, Anna, Tentler, John J., Pitts, Todd M., Tan, Aik Choon, Gregory, Mark A., Arcaroli, John J., Klauck, Peter J., McManus, Martine C., Hansen, Ryan J., Kim, Jihye, Micel, Lindsey N., Selby, Heather M., Newton, Timothy P., McPhillips, Kelly, Gustafson, Daniel L., DeGregori, James V., Messersmith, Wells A., Winn, Robert A., Eckhardt, S. Gail
Publicado em 2013