Systems biology approaches for advancing the discovery of effective drug combinations

Por Ryall, Karen A, Tan, Aik Choon
Publicado no J Cheminform (2015)

Automatic Context-Specific Subnetwork Discovery from Large Interaction Networks

Por Saha, Ashis, Tan, Aik Choon, Kang, Jaewoo
Publicado em 2014

Big Data Mining and Adverse Event Pattern Analysis in Clinical Drug Trials

Por Federer, Callie, Yoo, Minjae, Tan, Aik Choon
Publicado no Assay Drug Dev Technol (2016)

Exploiting receptor tyrosine kinase co-activation for cancer therapy

Por Tan, Aik-Choon, Vyse, Simon, Huang, Paul H
Publicado no Drug Discov Today (2016)

K-Map: connecting kinases with therapeutics for drug repurposing and development

Por Kim, Jihye, Yoo, Minjae, Kang, Jaewoo, Tan, Aik Choon
Publicado em 2013

iCOSSY: An Online Tool for Context-Specific Subnetwork Discovery from Gene Expression Data

Por Saha, Ashis, Jeon, Minji, Tan, Aik Choon, Kang, Jaewoo
Publicado no PLoS One (2015)

A Survey of Computational Tools to Analyze and Interpret Whole Exome Sequencing Data

Por Hintzsche, Jennifer D., Robinson, William A., Tan, Aik Choon
Publicado no Int J Genomics (2016)

Merging microarray data from separate breast cancer studies provides a robust prognostic test

Por Xu, Lei, Tan, Aik Choon, Winslow, Raimond L, Geman, Donald
Publicado em 2008

A genetic screen identifies TCF3/E2A and TRIAP1 as pathway-specific regulators of the cellular response to p53 activation

Por Andrysik, Zdenek, Kim, Jihye, Tan, Aik Choon, Espinosa, Joaquín M.
Publicado em 2013

PKCδ regulates integrin α(V)β(3) expression and transformed growth of K-ras dependent lung cancer cells

Por Symonds, Jennifer M., Ohm, Angela M., Tan, Aik-Choon, Reyland, Mary E.
Publicado no Oncotarget (2016)

Simple decision rules for classifying human cancers from gene expression profiles

Por Tan, Aik Choon, Naiman, Daniel Q., Xu, Lei, Winslow, Raimond L., Geman, Donald
Publicado em 2005

From Bench to Bedside: Lessons Learned in Translating Preclinical Studies in Cancer Drug Development

Por Lieu, Christopher H., Tan, Aik-Choon, Leong, Stephen, Diamond, Jennifer R., Eckhardt, S. Gail
Publicado em 2013

Confident Predictability: Identifying reliable gene expression patterns for individualized tumor classification using a local minimax kernel algorithm

Por Jones, Lee K, Zou, Fei, Kheifets, Alexander, Rybnikov, Konstantin, Berry, Damon, Tan, Aik Choon
Publicado em 2011

Integrating heterogeneous drug sensitivity data from cancer pharmacogenomic studies

Por Pozdeyev, Nikita, Yoo, Minjae, Mackie, Ryan, Schweppe, Rebecca E., Tan, Aik Choon, Haugen, Bryan R.
Publicado no Oncotarget (2016)

Host response transcriptional profiling reveals extracellular components and ABC (ATP-binding cassette) transporters gene enrichment in typhoid fever-infected Nigerian children

Por Khoo, Sok Kean, Petillo, David, Parida, Mrutyunjaya, Tan, Aik Choon, Resau, James H, Obaro, Stephen K
Publicado em 2011

A survey of statistical software for analysing RNA-seq data

Por Gao, Dexiang, Kim, Jihye, Kim, Hyunmin, Phang, Tzu L, Selby, Heather, Tan, Aik Choon, Tong, Tiejun
Publicado em 2010

Long Term Storage of Dry versus Frozen RNA for Next Generation Molecular Studies

Por Seelenfreund, Eric, Robinson, William A., Amato, Carol M., Tan, Aik-Choon, Kim, Jihye, Robinson, Steven E.
Publicado no PLoS One (2014)

Comparative haploid genetic screens reveal divergent pathways in the biogenesis and trafficking of glycophosphatidylinositol-anchored proteins

Por Davis, Eric M., Kim, Jihye, Menasche, Bridget, Sheppard, Jacob, Liu, Xuedong, Tan, Aik-Choon, Shen, Jingshi
Publicado no Cell Rep (2015)

BRONCO: Biomedical entity Relation ONcology COrpus for extracting gene-variant-disease-drug relations

Por Lee, Kyubum, Lee, Sunwon, Park, Sungjoon, Kim, Sunkyu, Kim, Suhkyung, Choi, Kwanghun, Tan, Aik Choon, Kang, Jaewoo
Publicado no Database (Oxford) (2016)

The IGF-1R/IR Tyrosine Kinase Inhibitor, PQIP, Exhibits Enhanced Anti-Tumor Effects in Combination with Chemotherapy Against Colorectal Cancer Models

Por Flanigan, Sara A., Pitts, Todd M., Eckhardt, S. Gail, Tentler, John J., Tan, Aik Choon, Thorburn, Andrew, Leong, Stephen
Publicado em 2010