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Systems biology approaches for advancing the discovery of effective drug combinations
Complex diseases like cancer are regulated by large, interconnected networks with many pathways affecting cell proliferation, invasion, and drug resistance. However, current cancer therapy predominantly relies on the reductionist approach of one gene-one disease. Combinations of drugs may overcome d...
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| Gepubliceerd in: | J Cheminform |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Springer International Publishing
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4348553/ https://ncbi.nlm.nih.gov/pubmed/25741385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-015-0055-9 |
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