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Comparative haploid genetic screens reveal divergent pathways in the biogenesis and trafficking of glycophosphatidylinositol-anchored proteins

Glycophosphatidylinositol-anchored proteins (GPI-APs) play essential roles in physiology but their biogenesis and trafficking have not been systematically characterized. Here, we took advantage of the recently available haploid genetics approach to dissect GPI-AP pathways in human cells, using prion...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Davis, Eric M., Kim, Jihye, Menasche, Bridget, Sheppard, Jacob, Liu, Xuedong, Tan, Aik-Choon, Shen, Jingshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481156/
https://ncbi.nlm.nih.gov/pubmed/26074080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.026
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