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Prion Proteins Without the Glycophosphatidylinositol Anchor: Potential Biomarkers in Neurodegenerative Diseases

Prion protein (PrP) is a biomolecule that is involved in neuronal signaling, myelinization, and the development of neurodegenerative diseases. In the cell, PrP is shed by the ADAM10 protease. This process generates PrP molecules that lack glycophosphatidylinositol anchor, and these molecules incorpo...

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Bibliografiske detaljer
Udgivet i:Biomark Insights
Main Authors: Kovač, Valerija, Čurin Šerbec, Vladka
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808966/
https://ncbi.nlm.nih.gov/pubmed/29449775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1177271918756648
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