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PKCδ regulates integrin α(V)β(3) expression and transformed growth of K-ras dependent lung cancer cells
We have previously shown that Protein Kinase C delta (PKCδ) functions as a tumor promoter in non-small cell lung cancer (NSCLC), specifically in the context of K-ras addiction. Here we define a novel PKCδ -> integrin α(V)β(3)->Extracellular signal-Regulated Kinase (ERK) pathway that regulates...
Sparad:
I publikationen: | Oncotarget |
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Huvudupphovsmän: | , , , |
Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
Impact Journals LLC
2016
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4951259/ https://ncbi.nlm.nih.gov/pubmed/26918447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7560 |
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