Src, PKCα, and PKCδ are required for αvβ3 integrin-mediated metastatic melanoma invasion

BACKGROUND: Integrins, cell-surface receptors that mediate adhesive interactions between cells and the extracellular matrix (ECM), play an important role in cancer progression. Expression of the vitronectin receptor αvβ3 integrin correlates with increased invasive and metastatic capacity of malignan...

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Detalhes bibliográficos
Main Authors: Putnam, Andrew J, Schulz, Veronique V, Freiter, Eric M, Bill, Heather M, Miranti, Cindy K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683837/
https://ncbi.nlm.nih.gov/pubmed/19400942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-7-10
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