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TYROSINE PHOSPHORYLATION REGULATES NUCLEAR TRANSLOCATION OF PKCδ

PKCδ is essential for apoptosis, but regulation of the proapoptotic function of this ubiquitous kinase is not well understood. Nuclear translocation of PKCδ is necessary and sufficient to induce apoptosis and is mediated via a C-terminal bipartite nuclear localization sequence. However, PKCδ is foun...

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Detalhes bibliográficos
Main Authors: Humphries, M. J., Ohm, A. M., Schaack, J., Adwan, T. S., Reyland, M. E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285468/
https://ncbi.nlm.nih.gov/pubmed/18059334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210967
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