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TYROSINE PHOSPHORYLATION REGULATES NUCLEAR TRANSLOCATION OF PKCδ
PKCδ is essential for apoptosis, but regulation of the proapoptotic function of this ubiquitous kinase is not well understood. Nuclear translocation of PKCδ is necessary and sufficient to induce apoptosis and is mediated via a C-terminal bipartite nuclear localization sequence. However, PKCδ is foun...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285468/ https://ncbi.nlm.nih.gov/pubmed/18059334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210967 |
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