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Nuclear import of PKCδ is required for apoptosis: identification of a novel nuclear import sequence
We have shown previously that protein kinase Cδ (PKCδ) is required for mitochondrial-dependent apoptosis. Here we show that PKCδ is imported into the nucleus of etoposide-treated cells, that nuclear import is required for apoptosis and that it is mediated by a nuclear localization signal (NLS) in th...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137198/ https://ncbi.nlm.nih.gov/pubmed/12426377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf606 |
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