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Multifunctional roles of PKCδ: Opportunities for targeted therapy in human disease
The serine–threonine protein kinase, protein kinase C-δ (PKCδ), is emerging as a bi-functional regulator of cell death and proliferation. Studies in PKCδ−/− mice have confirmed a pro-apoptotic role for this kinase in response to DNA damage and a tumor promoter role in some oncogenic contexts. In non...
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| Publicado en: | Pharmacol Ther |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5116389/ https://ncbi.nlm.nih.gov/pubmed/27179744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2016.05.001 |
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