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Functional proteomic analysis reveals roles for PKCδ in regulation of cell survival and cell death: Implications for cancer pathogenesis and therapy

Protein Kinase C-δ (PKCδ), regulates a broad group of biological functions and disease processes, including well-defined roles in immune function, cell survival and apoptosis. PKCδ primarily regulates apoptosis in normal tissues and non-transformed cells, and genetic disruption of the PRKCD gene in...

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Détails bibliographiques
Publié dans:Adv Biol Regul
Auteurs principaux: Speidel, Jordan T., Affandi, Trisiani, Jones, David N.M., Ferrara, Sarah E., Reyland, Mary E.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8294469/
https://ncbi.nlm.nih.gov/pubmed/33045516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2020.100757
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