Differential Roles of the PKC Novel Isoforms, PKCδ and PKCε, in Mouse and Human Platelets

BACKGROUND: Increasing evidence suggests that individual isoforms of protein kinase C (PKC) play distinct roles in regulating platelet activation. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we focus on the role of two novel PKC isoforms, PKCδ and PKCε, in both mouse and human platelets. PKCδ is...

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Bibliographic Details
Main Authors: Pears, Catherine J., Thornber, Kelly, Auger, Jocelyn M., Hughes, Craig E., Grygielska, Beata, Protty, Majd B., Pearce, Andrew C., Watson, Steve P.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583049/
https://ncbi.nlm.nih.gov/pubmed/19030108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003793
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