Regulation of mTOR and S6K1 Activation by the nPKC isoforms, PKC(ε) and PKC(δ), in Adult Cardiac Muscle Cells

Activation of both mTOR and its downstream target, S6K1 (p70 S6 kinase) have been implicated to affect cardiac hypertrophy. Our earlier work, in a feline model of 1–48 h pressure overload, demonstrated that mTOR/S6K1 activation occurred primarily through a PKC/c-Raf pathway. To further delineate the...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Moschella, Phillip C., Rao, Vijay U., McDermott, Paul J., Kuppuswamy, Dhandapani
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2170873/
https://ncbi.nlm.nih.gov/pubmed/17976640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.09.015
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky