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mTOR Complexes Repress Hypertrophic Agonist-Stimulated Expression of Connective Tissue Growth Factor in Adult Cardiac Muscle Cells
Connective tissue growth factor (CTGF) is a fibrogenic cytokine that promotes fibrosis in various organs. In the heart, both cardiomyocytes (CM) and cardiac fibroblasts (CFb) have been reported as a source of CTGF expression, aiding cardiac fibrosis. Since the mammalian target of rapamycin (mTOR) fo...
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| Publicado no: | J Cardiovasc Pharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7334753/ https://ncbi.nlm.nih.gov/pubmed/26371948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000322 |
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