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mTOR Complex 2 mediates Akt Phosphorylation that Requires PKCε in Adult Cardiac Muscle Cells

Our earlier work showed that mammalian target of rapamycin (mTOR) is essential to the development of various hypertrophic responses, including cardiomyocyte survival. mTOR forms two independent complexes, mTORC1 and mTORC2, by associating with common and distinct cellular proteins. Both complexes ar...

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Autors principals: Moschella, Phillip C., McKillop, John, Pleasant, Dorea L., Harston, Rebecca K., Balasubramanian, Sundaravadivel, Kuppuswamy, Dhandapani
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704180/
https://ncbi.nlm.nih.gov/pubmed/23673367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.05.001
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