Opposed Actions of PKA Isozymes (RI and RII) and PKC Isoforms (cPKCβI and nPKCε) in Neuromuscular Developmental Synapse Elimination

Background: During neuromuscular junction (NMJ) development, synapses are produced in excess. By sensing the activity-dependent release of ACh, adenosine, and neurotrophins, presynaptic receptors prompt axonal competition and loss of the unnecessary axons. The receptor action is mediated by synergis...

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Pubblicato in:Cells
Autori principali: Garcia, Neus, Balañà, Cori, Lanuza, Maria A., Tomàs, Marta, Cilleros-Mañé, Víctor, Just-Borràs, Laia, Tomàs, Josep
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912401/
https://ncbi.nlm.nih.gov/pubmed/31652775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8111304
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