PKCδ inhibition enhances tyrosine hydroxylase phosphorylation in mice after methamphetamine treatment

The present study was designed to evaluate the specific role of protein kinase C (PKC) δ in methamphetamine (MA)-induced dopaminergic toxicity. A multiple-dose administration regimen of MA significantly increases PKCδ expression, while rottlerin, a PKCδ inhibitor, significantly attenuates MA-induced...

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Detalhes bibliográficos
Main Authors: Shin, Eun-Joo, Duong, Chu Xuan, Nguyen, Xuan-Khanh Thi, Bing, Guoying, Bach, Jae-Hyung, Park, Dae Hun, Nakayama, Keiichi, Ali, Syed F., Kanthasamy, Anumantha G., Cadet, Jean L., Nabeshima, Toshitaka, Kim, Hyoung-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959171/
https://ncbi.nlm.nih.gov/pubmed/21672585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2011.03.022
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