Role of oxidative stress in methamphetamine-induced dopaminergic toxicity mediated by protein kinase Cδ

This study examined the role of protein kinase C (PKC) isozymes in methamphetamine (MA)-induced dopaminergic toxicity. Multiple-dose administration of MA did not significantly alter PKCα, PKCβI, PKCβII, or PKCζ expression in the striatum, but did significantly increase PKCδ expression. Gö6976 (a co-...

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Autors principals: Shin, Eun-Joo, Duong, Chu Xuan, Nguyen, Xuan-Khanh Thi, Li, Zhengyi, Bing, Guoying, Bach, Jae-Hyung, Park, Dae Hun, Nakayama, Keiichi, Ali, Syed F., Kanthasamy, Anumantha G., Cadet, Jean Lud, Nabeshima, Toshitaka, Kim, Hyoung-Chun
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964682/
https://ncbi.nlm.nih.gov/pubmed/22512859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2012.04.001
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