Thyroid cancer cell lines: Critical models to study thyroid cancer biology and new therapeutic targets

Por Schweppe, Rebecca E.
Publicado em 2012

Thyroid Cancer Cell Line Misidentification: An Update

Por Schweppe, Rebecca E.
Publicado em 2013

Pituitary Ets-1 and GABP bind to the growth factor regulatory sites of the rat prolactin promoter

Por Schweppe, Rebecca E., Gutierrez-Hartmann, Arthur
Publicado em 2001

Inhibition of nuclear factor-kappa B differentially affects thyroid cancer cell growth, apoptosis, and invasion

Por Bauerle, Kevin T, Schweppe, Rebecca E, Haugen, Bryan R
Publicado em 2010

Molecular Therapeutics for Anaplastic Thyroid Cancer

Por Pozdeyev, Nikita, Rose, Madison M., Bowles, Daniel W., Schweppe, Rebecca E.
Publicado no Semin Cancer Biol (2020)

Integrating heterogeneous drug sensitivity data from cancer pharmacogenomic studies

Por Pozdeyev, Nikita, Yoo, Minjae, Mackie, Ryan, Schweppe, Rebecca E., Tan, Aik Choon, Haugen, Bryan R.
Publicado no Oncotarget (2016)

Genetics of Human Thyroid Cancer Cell Lines—Response

Por Landa, Iñigo, Pozdeyev, Nikita, Knauf, Jeffrey A., Haugen, Bryan R., Fagin, James A., Schweppe, Rebecca E.
Publicado no Clin Cancer Res (2019)

Inhibition of Src with AZD0530 Reveals the Src-Focal Adhesion Kinase Complex as a Novel Therapeutic Target in Papillary and Anaplastic Thyroid Cancer

Por Schweppe, Rebecca E., Kerege, Anna A., French, Jena D., Sharma, Vibha, Grzywa, Rachel L., Haugen, Bryan R.
Publicado em 2009

Inhibition of Src with AZD0530 Reveals the Src-Focal Adhesion Kinase Complex as a Novel Therapeutic Target in Papillary and Anaplastic Thyroid Cancers

Por Schweppe, Rebecca E., Kerege, Anna A., French, Jena D., Sharma, Vibha, Grzywa, Rachel L., Haugen, Bryan R.
Publicado no Mol Endocrinol (2009)

Distinct Genetic Alterations in the Mitogen-Activated Protein Kinase Pathway Dictate Sensitivity of Thyroid Cancer Cells to Mitogen-Activated Protein Kinase Kinase 1/2 Inhibition

Por Schweppe, Rebecca E., Kerege, Anna A., Sharma, Vibha, Poczobutt, Joanna M., Gutierrez-Hartmann, Arthur, Grzywa, Rachel L., Haugen, Bryan R.
Publicado em 2009

Sustained activation of the AKT/mTOR and MAP kinase pathways mediate resistance to the Src inhibitor, dasatinib, in thyroid cancer

Por Mishall, Katie M., Beadnell, Thomas C., Kuenzi, Brent M., Klimczak, Dorothy M., Superti-Furga, Giulio, Rix, Uwe, Schweppe, Rebecca E.
Publicado no Oncotarget (2017)

PPARγ Promotes Growth and Invasion of Thyroid Cancer Cells

Por Wood, William M., Sharma, Vibha, Bauerle, Kevin T., Pike, Laura A., Zhou, Qiong, Fretwell, Deborah L., Schweppe, Rebecca E., Haugen, Bryan R.
Publicado em 2011

Nuclear Factor κB–Dependent Regulation of Angiogenesis, and Metastasis in an In Vivo Model of Thyroid Cancer Is Associated With Secreted Interleukin-8

Por Bauerle, Kevin T., Schweppe, Rebecca E., Lund, Gregory, Kotnis, Gregory, Deep, Gagan, Agarwal, Rajesh, Pozdeyev, Nikita, Wood, William M., Haugen, Bryan R.
Publicado em 2014

FAK Expression, Not Kinase Activity, is a Key Mediator of Thyroid Tumorigenesis and Pro-tumorigenic Processes

Por Kessler, Brittelle E., Sharma, Vibha, Zhou, Qiong, Jing, Xia, Pike, Laura A., Kerege, Anna A., Sams, Sharon B., Schweppe, Rebecca E.
Publicado no Mol Cancer Res (2016)

Cytostatic Activity of Adenosine Triphosphate-Competitive Kinase Inhibitors in BRAF Mutant Thyroid Carcinoma Cells

Por Salerno, Paolo, De Falco, Valentina, Tamburrino, Anna, Nappi, Tito Claudio, Vecchio, Giancarlo, Schweppe, Rebecca E., Bollag, Gideon, Santoro, Massimo, Salvatore, Giuliana
Publicado no Mol Endocrinol (2009)

Src-mediated regulation of the PI3K pathway in advanced papillary and anaplastic thyroid cancer

Por Beadnell, Thomas C., Nassar, Kelsey W., Rose, Madison M., Clark, Erin G., Danysh, Brian P., Hofmann, Marie-Claude, Pozdeyev, Nikita, Schweppe, Rebecca E.
Publicado no Oncogenesis (2018)

Characterization of Thyroid Cancer Cell Lines in Murine Orthotopic and Intracardiac Metastasis Models

Por Morrison, Jennifer A., Pike, Laura A., Lund, Greg, Zhou, Qiong, Kessler, Brittelle E., Bauerle, Kevin T., Sams, Sharon B., Haugen, Bryan R., Schweppe, Rebecca E.
Publicado no Horm Cancer (2015)

Resistance to Src inhibition alters the BRAF-mutant tumor secretome to promote an invasive phenotype and therapeutic escape through a FAK>p130Cas>c-Jun signaling axis

Por Kessler, Brittelle E., Mishall, Katie M., Kellett, Meghan D., Clark, Erin G., Pugazhenthi, Umarani, Pozdeyev, Nikita, Kim, Jihye, Tan, Aik Choon, Schweppe, Rebecca E.
Publicado no Oncogene (2018)

Targeted Inhibition of Src Kinase with Dasatinib Blocks Thyroid Cancer Growth and Metastasis

Por Chan, Christine M., Jing, Xia, Pike, Laura A., Zhou, Qiong, Lim, Dong-Jun, Sams, Sharon B., Lund, Gregory S., Sharma, Vibha, Haugen, Bryan R., Schweppe, Rebecca E.
Publicado em 2012

Deoxyribonucleic Acid Profiling Analysis of 40 Human Thyroid Cancer Cell Lines Reveals Cross-Contamination Resulting in Cell Line Redundancy and Misidentification

Por Schweppe, Rebecca E., Klopper, Joshua P., Korch, Christopher, Pugazhenthi, Umarani, Benezra, Miriam, Knauf, Jeffrey A., Fagin, James A., Marlow, Laura A., Copland, John A., Smallridge, Robert C., Haugen, Bryan R.
Publicado em 2008