Загрузка...
Resistance to Src inhibition alters the BRAF-mutant tumor secretome to promote an invasive phenotype and therapeutic escape through a FAK>p130Cas>c-Jun signaling axis
Few therapy options exist for patients with advanced papillary and anaplastic thyroid cancer. We and others have previously identified c-Src as a key mediator of thyroid cancer pro-tumorigenic processes and a promising therapeutic target for thyroid cancer. To increase the efficacy of targeting Src...
Сохранить в:
| Опубликовано в: : | Oncogene |
|---|---|
| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6450711/ https://ncbi.nlm.nih.gov/pubmed/30531837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0617-1 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|