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The Mitogen Activated Protein Kinase Pathway Facilitates Resistance to the Src Inhibitor, Dasatinib, in Thyroid Cancer

Advanced stages of papillary and anaplastic thyroid cancer represent a highly aggressive subset, in which there are currently few effective therapies. We and others have recently demonstrated that c-Src is a key mediator of growth, invasion, and metastasis, and therefore represents a promising thera...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Beadnell, Thomas C., Mishall, Katie M., Zhou, Qiong, Riffert, Stephen M., Wuensch, Kelsey E., Kessler, Brittelle E., Corpuz, Maia L., Jing, Xia, Kim, Jihye, Wang, Guoliang, Tan, Aik Choon, Schweppe, Rebecca E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975658/
https://ncbi.nlm.nih.gov/pubmed/27222538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0702
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