p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is an aggressive disease with a poor prognosis. Advances in the treatment of TNBC have been hampered by the lack of novel effective targeted therapies. The primary goal of this study was to evaluate the efficacy of targeting Aurora kinase A (AurA), a key regulato...

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Vydáno v:Mol Cancer Ther
Hlavní autoři: Tentler, John J., Ionkina, Anastasia, Tan, Aik Choon, Newton, Timothy P., Pitts, Todd M., Glogowska, Magdalena J., Kabos, Peter, Sartorius, Carol A., Sullivan, Kelly D., Espinosa, Joaquin M., Eckhardt, S. Gail, Diamond, Jennifer R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425647/
https://ncbi.nlm.nih.gov/pubmed/25758253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0538-T
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