Antitrypsin Deficiency, the Serpinopathies, and Chronic Obstructive Pulmonary Disease

Por Lomas, David A.
Publicado em 2006

Molecular mousetraps, α(1)-antitrypsin deficiency and the serpinopathies

Por Lomas, David A
Publicado no Clin Med (Lond) (2005)

Genetic predisposition to chronic obstructive pulmonary disease: advances in α(1)-antitrypsin deficiency and the serpinopathies

Por Lomas, David A
Publicado no Clin Med (Lond) (2007)

α(1)-Antitrypsin polymerization and the serpinopathies: pathobiology and prospects for therapy

Por Lomas, David A., Mahadeva, Ravi
Publicado em 2002

Polymers and inflammation: disease mechanisms of the serpinopathies

Por Gooptu, Bibek, Lomas, David A.
Publicado em 2008

Stem cell-based therapy for α(1)-antitrypsin deficiency

Por Rashid, S Tamir, Lomas, David A
Publicado em 2012

The genetics of chronic obstructive pulmonary disease

Por Silverman Edwin K, Lomas David A
Publicado em 2001-01-01

The genetics of chronic obstructive pulmonary disease

Por Lomas, David A, Silverman, Edwin K
Publicado em 2001

Why has it been so difficult to prove the efficacy of alpha-1-antitrypsin replacement therapy? Insights from the study of disease pathogenesis

Por Dickens, Jennifer A, Lomas, David A
Publicado em 2011

pH-dependent stability of neuroserpin is mediated by histidines 119 and 138; Implications for the control of β-sheet A and polymerization

Por Belorgey, Didier, Hägglöf, Peter, Onda, Maki, Lomas, David A
Publicado em 2010

Protein Misfolding and the Serpinopathies

Por Belorgey, Didier, Hägglöf, Peter, Karlsson-Li, Susanna, Lomas, David A
Publicado em 2007

Alzheimer's disease: insights from Drosophila melanogaster models

Por Moloney, Aileen, Sattelle, David B., Lomas, David A., Crowther, Damian C.
Publicado em 2010

The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer’s disease

Por Chen, Ko-Fan, Possidente, Bernard, Lomas, David A., Crowther, Damian C.
Publicado em 2014

Altered native stability is the dominant basis for susceptibility of α(1)-antitrypsin mutants to polymerization

Por Irving, James A., Haq, Imran, Dickens, Jennifer A., Faull, Sarah V., Lomas, David A.
Publicado em 2014

Endoplasmic reticulum polymers impair luminal protein mobility and sensitise to cellular stress in α(1)-antitrypsin deficiency

Por Ordóñez, Adriana, Snapp, Erik L, Tan, Lu, Miranda, Elena, Marciniak, Stefan J, Lomas, David A
Publicado em 2013

Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease

Por Duvoix, Annelyse, Dickens, Jenny, Haq, Imran, Mannino, David, Miller, Bruce, Tal-Singer, Ruth, Lomas, David A
Publicado em 2013

Neuroserpin Polymers Activate NF-κB by a Calcium Signaling Pathway That Is Independent of the Unfolded Protein Response

Por Davies, Mark J., Miranda, Elena, Roussel, Benoit D., Kaufman, Randal J., Marciniak, Stefan J., Lomas, David A.
Publicado em 2009

The iFly Tracking System for an Automated Locomotor and Behavioural Analysis of Drosophila melanogaster

Por Kohlhoff, Kai J., Jahn, Thomas R., Lomas, David A., Dobson, Christopher M., Crowther, Damian C., Vendruscolo, Michele
Publicado no Integr Biol (Camb) (2011)

COPD association and repeatability of blood biomarkers in the ECLIPSE cohort

Por Dickens Jennifer A, Miller Bruce E, Edwards Lisa D, Silverman Edwin K, Lomas David A, Tal-Singer Ruth
Publicado em 2011-11-01

Clinical outcome in relation to care in centres specialising in cystic fibrosis: cross sectional study

Por Mahadeva, Ravi, Webb, Kevin, Westerbeek, Roger C, Carroll, Nick R, Dodd, Mary E, Bilton, Diana, Lomas, David A
Publicado em 1998