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Protein Misfolding and the Serpinopathies

The serpins are the largest superfamily of protease inhibitors. They are found in almost all branches of life including viruses, prokaryotes and eukaryotes. They inhibit their target protease by a unique mechanism that involves a large conformational transition and the translocation of the enzyme fr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Belorgey, Didier, Hägglöf, Peter, Karlsson-Li, Susanna, Lomas, David A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633702/
https://ncbi.nlm.nih.gov/pubmed/19164889
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