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Antitrypsin Deficiency, the Serpinopathies, and Chronic Obstructive Pulmonary Disease
α(1)-Antitrypsin deficiency is the only genetic factor that is widely recognized to predispose smokers to chronic obstructive pulmonary disease. We have shown that the plasma deficiency results from point mutations perturbing the structure of the protein to favor sequential linkage between the react...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Thoracic Society
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643219/ https://ncbi.nlm.nih.gov/pubmed/16921127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.200603-069MS |
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